Resistance Training Enhances Renal Function in Experimental Renal Ischemia-Reperfusion

Acute kidney injury (AKI) resulting from ischemia-reperfusion (IRI) is among the most common complications in hospitalized patients. In recent years, it has been argued that exercise an approach to attenuate impairments caused by AKI. The purpose of this study was investigate whether eight weeks resistance training (RT) protective effects on IRI. Thirty male Wistar rats (210-230 g) were randomly divided into four groups, including RT+ISC (n=7), RT (n=8), ISC and sham (n=8). Animals underwent RT, 48 hours after last session, ischemia (45 min) reperfusion (24 h) induced. Then animals sacrificed, blood tissue samples collected measure creatinine (Cr), urea nitrogen (BUN), damage score (KTDS), weight (KW). results showed IRI a significant increase Cr, BUN, KTDS, KW (p-value <0.05), while decreased severity BUN remarkably. (p≤0.05). however, did not Overall, findings our provide evidence can IRI-induced AKI considering enhanced biomarkers; However, further research should be conducted make certain about training, especially RT.